Skip to content
Property for sale at 2110 4TH STREET E, PALMETTO, FL, 34221
Property for sale at 2110 4TH STREET E, PALMETTO, FL, 34221
1 / 37

2110 4th Street EPalmetto, FL, 34221

4beds
4baths
3,034sqft
Single Family Residence
Built in 2022
$1,895 Annually HOA Fee
$1,350,000
For sale
Price per sqft
$445
Days on market
2
Listed
Nov 5
MLS #TB8557202Updated Nov 7, 2026

About this property

Virtually Staged. Nestled within the prestigious gated community of Water’s Edge at Sanctuary Cove, this custom-built waterfront residence offers the beauty of life on the water, the privacy of a peaceful retreat, and the added peace of mind that comes with newer construction and a Generac whole-house generator. Built in 2022, the home features over 3,000 square feet of living space, four bedrooms plus an office, a private primary retreat with patio access, three full bathrooms, a spacious kitchen with a Forno gas range and peninsula seating that flows seamlessly into the open family room. Let the outdoors in with two sets of French doors that open between the family room and the outdoor covered patio with an outdoor kitchen providing a perfect set up for entertaining. Boasting 110 feet of FRESHWATER canal frontage, a private dock with a 13,000-pound boat lift, and access through the community canal system to the Manatee River and surrounding waterways, this home is a boater's dream. Enjoy a fully fenced backyard designed for relaxation and entertaining, featuring a sparkling pool with bubblers, a sun shelf with an umbrella, expansive paver patios, inviting outdoor dining and lounge areas, and generous lawn space. Together, these elements create an idyllic setting for sun-filled afternoons, intimate gatherings, and peaceful evenings overlooking the water. Another unique feature of this residence is the two separate car garages; one car and a two car, each with its own private entrance, offering a unique arrangement for extended family or guests. Beyond your private oasis, Sanctuary Cove delivers a resort-inspired lifestyle with a gated entrance, waterfront marina, resort-style pool and a clubhouse, fitness center, playground, dog park, and beautiful riverfront gathering areas. Enjoy the surrounding waterways of Terra Ceia Bay and the Manatee River, with access to the boating and coastal lifestyle that makes this area so desirable. Conveniently located directly across the street from the popular Detwiler's Fresh Farm Market and just minutes from historic downtown Palmetto, Bradenton, Sarasota, St. Petersburg, and Tampa, this property offers the perfect balance of peaceful waterfront living and everyday convenience. Don't miss this opportunity to experience the best of Florida waterfront living at Sanctuary Cove!

Top Villas Intelligence

Projected rental revenue and ownership costs
Sign in to view rental intelligenceSee projected rental revenue, ownership costs, operating yield, and supporting evidence.
Interested in this property?
Gaby, Property Specialist
Speak to GabyProperty Specialist, SerhantGaby can arrange a viewing, answer your questions and prepare a personalized rental projection.
+1 (407) 490-0475
No pressure. Your details stay private.

Property details

Property type
Single Family Residence
Street address
2110 4th Street E
City
Palmetto
State
FL
ZIP code
34221
Year built
2022
New construction
No
Attached property
No
Faces
South
Rooms
4
Living area
3,034 sqft
Total building area
3,034 sqft
Architectural style
Contemporary
Levels
One

Stellar MLSThe data relating to real estate displayed on this website comes in part from the Internet Data Exchange (IDX) Program of Stellar MLS. All listing information is deemed reliable but not guaranteed and should be independently verified through personal inspection by appropriate professionals. Listings displayed on this website may be subject to prior sale or removal from sale; the availability of any listing should always be independently verified. Listing information is provided for consumers' personal, non-commercial use, solely to identify potential properties for potential purchase; all other use is strictly prohibited and may violate relevant federal and state law.Stellar (MFR) data last updated at November 7, 2026 at 9:30 PM EST

Price & sale history

EventPrice
Listed for saleMLS #TB8557202$1,350,000
History may be incomplete.
Explore nearby sales

Location

Property for sale at 2110 4TH STREET E, PALMETTO, FL, 34221
Learn more about this propertyGet in touch for more information
We will use your details to respond to this request and may share them with a suitable real estate professional when needed. Marketing is optional.